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Advances in degradomics technologies to assess proteolytic cleavage events | Synapse
March 3, 2026
Advances in degradomics technologies to assess proteolytic cleavage events
AZ
A. Ziegler
NS
Nichollas E. Scott
University of Technology Sydney
LE
Laura E. Edgington-Mitchell
Key Points
Key biomarkers show significant changes during proteolytic cleavage, indicating potential regulatory functions.
Analysis reveals that mass spectrometry can accurately assess proteolytic events across diverse biological systems.
Innovative degradomics technologies enhance understanding of molecular pathways linked to protein function.
These insights may enable new strategies for therapeutic intervention targeting proteolysis.
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Ziegler et al. (Sun,) studied this question.
synapsesocial.com/papers/69a765ffbadf0bb9e87db37c
https://doi.org/https://doi.org/10.1016/j.chembiol.2026.01.001