Integrated multi-omics analysis reveals flavonoid-driven mechanisms underlying callus browning in Cunninghamia lanceolata

Key Points

• Callus browning mechanisms are influenced primarily by flavonoid compounds, highlighting their role.
• Flavonoid concentrations were significantly altered, with notable changes in gene expression and metabolites.
• Multi-omics analysis combining genomics, transcriptomics, and metabolomics was utilized for comprehensive insights.
• Understanding these mechanisms may improve strategies for managing browning, particularly in plant biotechnology.