Thrombelastography-estimated functional fibrinogen in healthy volunteers, end-stage renal disease, and trauma: inaccurate when most needed

Key Points

• Functional fibrinogen measurements using thrombelastography may be inaccurate, especially in critical situations.
• Significant discrepancies were observed across patient groups, with end-stage renal disease patients showing notable variability.
• Assessment techniques included thrombelastography to evaluate coagulation status in diverse health conditions.
• Findings highlight the critical need for enhanced diagnostic accuracy in testing fibrogen levels, particularly in trauma emergencies.