March 3, 2026

Modeling Aeromonas Pathogenesis in C. elegans Using a Survival Assay

Key Points

Survival assay measures mortality in C. elegans following Aeromonas infection, revealing bacterial virulence.
The study shows that oral ingestion of Aeromonas leads to significant intestinal infection in C. elegans.
Assessment utilizes a survival model in live host systems to quantify pathogenic effects and bacterial behavior.
Findings highlight the utility of C. elegans as a model organism for studying Aeromonas infections and their implications.

Abstract

Source: Chen, Y., et al. Evaluating Virulence and Pathogenesis of Aeromonas Infection in a Caenorhabditis elegans Model. J. Vis. Exp. (2018)This video demonstrates a survival assay using C. elegans to model Aeromonas pathogenesis, where oral ingestion of the bacteria leads to intestinal infection and mortality, enabling quantitative assessment of bacterial virulence in a live host system.

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Cite This Study

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synapsesocial.com/papers/69a7662bbadf0bb9e87dbf98 https://doi.org/https://doi.org/10.3791/24367

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