Ultrasound regulation of trypsin-enrofloxacin binding and conformational changes

Key Points

• Binding dynamics of trypsin with enrofloxacin are significantly altered by ultrasound exposure, enhancing interaction stability.
• Observed conformational changes of trypsin were quantified using spectroscopic techniques during ultrasound application.
• Assessment using ultrasound modulation revealed distinct binding affinities between trypsin and enrofloxacin.
• This highlights potential for ultrasound in enhancing drug-target interactions, warranting further exploration.