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Efferocytosis deficiency exacerbates local inflammation and predicts recurrence in chronic rhinosinusitis with nasal polyps | Synapse
March 3, 2026
Efferocytosis deficiency exacerbates local inflammation and predicts recurrence in chronic rhinosinusitis with nasal polyps
SL
Shuang Liang
BY
Bing Yan
SS
Shen Shen
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Key Points
Efferocytosis deficiency increases local inflammation in chronic rhinosinusitis with nasal polyps, impacting disease severity.
Local inflammation markers were observed to be elevated in subjects with efferocytosis deficiencies.
The study employs an observational analysis correlating efferocytosis levels with local inflammation and recurrence rates.
These findings indicate a need for further research into efferocytosis as a therapeutic target to reduce inflammation in nasal polyps.
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Liang et al. (Sun,) studied this question.
synapsesocial.com/papers/69a76678badf0bb9e87dd202
https://doi.org/https://doi.org/10.1016/j.jaci.2025.12.1016