Integrated study on anti-inflammatory and anti-atopic dermatitis efficacy of Saposhnikoviae Radix: UPLC-MS/GC-MS metabolomics and in vitro/in vivo experimental models

Key Points

• Saposhnikoviae radix shows significant anti-inflammatory activity in atopic dermatitis models, indicating its therapeutic potential.
• Key evidence reveals multiple beneficial compounds identified through UPLC-MS and GC-MS, enhancing the understanding of its effects.
• The study employs both in vitro and in vivo experimental models to validate the efficacy of the intervention in various settings.
• These findings highlight the potential for new treatments targeting inflammation, though further validation in clinical settings is necessary.