Diallyl disulfide suppresses weight gain, adipogenesis, and matrix metalloproteinases (MMPs) expression in high-fat-diet-induced obese animal model | Synapse
March 3, 2026Open Access
Diallyl disulfide suppresses weight gain, adipogenesis, and matrix metalloproteinases (MMPs) expression in high-fat-diet-induced obese animal model
Key Points
Weight gain is significantly suppressed by diallyl disulfide, impacting adipogenesis.
Diallyl disulfide appears to inhibit both MMP-2 and MMP-9, which are associated with fat accumulation.
Observational analysis in a high-fat diet-induced obesity model shows the effects in mice.
These findings suggest potential therapeutic benefits in managing obesity-related conditions.
Abstract
DADS suppressed body weight gain and adipogenesis, potentially by inhibiting MMP-2 and MMP-9 in mice fed a high-fat diet.