A regulatory role of novel long non-coding RNA, BAZ1A-AS1, in vascular smooth muscle cell functions during neointima formation in human saphenous veins

Key Points

• Neointima formation is influenced by the lncRNA BAZ1A-AS1, which plays a regulatory role in vascular smooth muscle cells.
• Key findings include the identification of the BAZ1A-AS1/BAZ1A axis as pivotal in neointima formation analysis.
• Analysis reveals the potential for BAZ1A-AS1 as a therapeutic target to prevent saphenous vein graft failure after CABG.
• These findings suggest new insights into molecular mechanisms, needing further investigation for possible clinical applications.