Computationally guided synthesis and biological profiling of chalcones as antioxidant and anti-inflammatory activities

Key Points

• Chalcones exhibit significant antioxidant and anti-inflammatory activities, enhancing their therapeutic potential.
• Specifically, compound analysis showed a 30% increase in antioxidant capacity compared to control samples.
• Computational synthesis techniques were utilized to design and evaluate chalcones for optimized biological activity.
• These findings highlight the relevance of computational methods in drug development, particularly for chalcone derivatives.