Copper oxide nanoparticles (CuO NPs) have emerged as a promising area of research due to their remarkable biological and medical properties. This investigation showcases an environmentally friendly method for synthesising CuO NPs using garden cress seed extract, which serves as both a reducing and stabilising agent. The study highlights the potential applications of CuO NPs as antioxidants, antifungal agents, and beta-hematin inhibitors. The synthesized CuO NPs underwent comprehensive characterization using various techniques, including UV-Vis spectroscopy, X-ray diffraction (XRD), Scanning Electron Microscopy (SEM), and Fourier transform infrared spectroscopy (FTIR). The antioxidant potential was assessed using the DPPH assay, while antifungal activities were investigated against specific pathogens. Additionally, the antimalarial activity was evaluated through beta-hematin inhibition studies. The results revealed that CuO NPs exhibited a distinctive absorption peak at 420 nm, indicative of their surface plasmon resonance property and a spherical shape with sizes ranging from 30 to 50 nm, as observed through SEM. Additionally, the resulting CuO NPs demonstrate significant antioxidant activity comparable to ascorbic acid, promising antifungal properties against Monosporascus cannonballus,and substantial activity against beta-hematin formation. The findings suggest that CuO NPs hold potential as therapeutic agents, warranting further research and development.
Ali et al. (Thu,) studied this question.