From ageing clocks to organ networks: Biological age-driven organ asynchrony and inter-organ interactions shaping mortality risk

Key Points

• Organ asynchrony is linked to increased mortality risk, highlighting the importance of ageing clocks.
• Biological age impacts inter-organ interactions, potentially affecting overall health and survival.
• Analysis of physiological systems shows how organ networks communicate and influence health outcomes through molecular pathways.
• Understanding these interactions may enable better predictions of mortality risk linked to aging.