Establishing a Zebrafish (Danio rerio) infection model to assess antimicrobial treatment efficacy against Staphylococcus aureus expressing the NorA efflux pump

Key Points

• Treatment efficacy assessments reveal significant outcomes using a zebrafish infection model, with notable results for staphylococcus aureus.
• The study emphasizes the critical role of the norA efflux pump in antimicrobial resistance, affecting treatment responses.
• Analysis focused on antimicrobial interventions tailored for staphylococcus aureus within a controlled zebrafish environment.
• Findings may enable enhanced understanding of infection responses, though confirmation in other models is needed.