RETRACTION: Melatonin Suppresses Proinflammatory Mediators in Lipopolysaccharide-Stimulated CRL1999 Cells via Targeting MAPK, NF-κB, c/EBPβ, and p300 Signaling.

D. Shi, X. Xiao, J. Wang, L. Liu, W. Chen, L. Fu, F. Xie, W. Huang, and W. Deng, "Melatonin Suppresses Proinflammatory Mediators in Lipopolysaccharide-Stimulated CRL1999 Cells via Targeting MAPK, NF-κB, c/EBPβ, and p300 Signaling," Journal of Pineal Research 53, no. 2 (2012): 154-165, https://doi.org/10.1111/j.1600-079X.2012.00982.x. The above article, published online on 30 January 2012 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the journal Editor-in-Chief, Gianluca Tosini; and John Wiley & Sons Ltd. A third party raised concerns that three of the four bands in the IL-1β image in Figure 1D were copied and presented as the COX-2 image in Figure 2B. An investigation by the publisher confirmed this duplication and also confirmed that the GAPDH control bands had been reused in both figures. The authors responded to an inquiry by the publisher, but they could not supply all of the original data for the article to validate the data. The retraction has been agreed to because the evidence of image duplication and manipulation in the article compromises the editors' confidence in the results presented. The authors were informed about the retraction.