What question did this study set out to answer?

To evaluate the cost effectiveness of the adjuvanted recombinant zoster vaccine (RZV) in preventing herpes zoster (HZ) in older adults in Portugal.

March 5, 2026Open Access

Cost Effectiveness of the Adjuvanted Recombinant Zoster Vaccine in Older Adults in Portugal

Key Points

To evaluate the cost effectiveness of the adjuvanted recombinant zoster vaccine (RZV) in preventing herpes zoster (HZ) in older adults in Portugal.
Economic evaluation of vaccine costs and health outcomes
Assessment of cost-effectiveness per age group
Comparison of RZV with standard prevention strategies
RZV is cost-effective for preventing HZ in adults aged 65 years and older.
Cost effectiveness increases for individuals aged 65-69 years due to reduced complication rates.

Abstract

RZV presents a cost-effective option for the prevention of HZ and its complications in Portuguese adults aged ≥ 65 years, with greater cost effectiveness in those aged 65-69 years.

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Discussion

Cite this study

Zarkadoulas et al. (Mon,) studied this question.

synapsesocial.com/papers/69a91cbed6127c7a504bfae8 — DOI: https://doi.org/10.1007/s41669-026-00640-3

Also consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

Updated Public Health Impact and Cost Effectiveness of Recombinant Zoster Vaccine in Canadian Adults Aged 50 Years and Older· 2024 · 4 citations
The public health impact of recombinant herpes zoster vaccination in adults over 50 years in Spain· 2024 · 4 citations
Herpes Zoster· 2013 · 702 citations
Quality-Adjusted Life Year (QALY) Losses Associated With Herpes Zoster And Postherpetic Neuralgia In Immunocompromised (IC) and IC-FREE Individuals AGED ≥50 Years of Age, In The Uk Population· 2017 · 1 citations
Cost Effectiveness of Quadrivalent Versus Trivalent Inactivated Influenza Vaccines for the Portuguese Elderly Population· 2022 · 2 citations

Authors

Eleftherios Zarkadoulas

GlaxoSmithKline (Belgium)

Fabio Luiz Carneiro Mourilhe Silva

Joana Alves

Journals

PharmacoEconomics - Open

Actions

Institutions

University of Groningen

University Medical Center Groningen

Universidade Nova de Lisboa

References and Citations

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Cost Effectiveness of the Adjuvanted Recombinant Zoster Vaccine in Older Adults in Portugal

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Cite this study

Also consider

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

Also consider