What question did this study set out to answer?

To develop and validate a simulation tool using GEANT4 for proton therapy dose distribution.

March 5, 2026Open Access

A New Monte Carlo - GEANT4 Simulation Tool for the Development of a Proton Therapy Beam Line and Verification of the Related Dose Distributions

Key Points

To develop and validate a simulation tool using GEANT4 for proton therapy dose distribution.
Simulated the hadron-therapy beam line of the CATANA center.
Modeled elements such as diffusers, range shifters, collimators, and detectors.
Conducted comparisons of simulated and experimental dose distributions.
Simulated ranges and energy distribution of the proton beams were effectively modeled.
Depth and lateral dose distributions were validated against experimental results.
Results indicate the software's capability to replicate experimental conditions successfully.

Abstract

Using the Monte Carlo simulation tool GEANT4 we simulated the hadron-therapy beam line of the CATANA (Centro di AdroTerapia ed Applicazioni Nucleari Avanzate) center. This is the unique italian hadron-therapy facility in which 62 MeV proton beams are used for the radiotherapeutic treatment of choroidal and iris melanomas. All the elements, such as diffusers, range shifters, collimators and detectors, typical of a proton-therapy line were modelled. The beam line provides an ideal environment for the experimental testing and validation of the software developed. The software architecture was developed, and the validation of the software is in its final stage. Simulated ranges, energy distribution, depth and lateral dose distributions for full energy proton beams will be compared tothe experimental results obtained at LNS (Laboratori Nazionali del Sud) with different detectors.

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