Sustained response off-treatment and thrombotic events in patients with immune thrombocytopenia treated with fostamatinib: a systematic review and meta-analysis

Key Points

• To evaluate the sustained response off-treatment and the occurrence of thrombotic events in patients with immune thrombocytopenia treated with fostamatinib.
• Conducted a systematic review of existing literature
• Performed a meta-analysis to synthesize data
• Included studies assessing treatment effects on thrombocytopenia
• Identified significant rates of sustained treatment response off-treatment
• Revealed a potential association with increased thrombotic events
• Highlighted inconsistent findings across studies regarding safety and efficacy.