Recent advances in functional polymer composites (FPCs) have transformed their role in biomedical science, with particular emphasis on methodological innovation and translational application. Advances in fabrication (additive manufacturing AM, electrospinning and in situ polymerisation) enable precise engineering of composite materials with multifunctional, stimuli-responsive and nanofiller-enhanced structures. These fabrication strategies have led to FPCs that exhibit superior bioactivity, mechanical strength and electrical performance, contributing directly to improved therapeutic efficacy in tissue engineering scaffolds, wound dressings, implantable medical devices and regenerative medicine. The integration of smart polymers and hybrid fillers has yielded composites with enhanced biosensing and targeted drug-delivery capabilities, enabling real-time interaction with biological environments and facilitating personalised medical care. Recent studies highlight the utility of FPCs in responding to physiological stimuli and in supporting complex cellular processes crucial for tissue regeneration. Despite significant progress, challenges remain regarding industrial scalability, regulatory approval and long-term biocompatibility. Research is increasingly directed towards sustainable processing methods and the development of personalised composite platforms, addressing both environmental and individual healthcare needs. By focusing on the latest perspective-driven outcomes and trends, this review underscores how emerging methodologies and interdisciplinary approaches are shaping the evolution of FPCs into next-generation solutions for precision medicine and healthcare innovation.
Issaka et al. (Thu,) studied this question.