What does this research mean for the field?

Underweight is associated with detectable viral load among adolescents with HIV in rural eastern Uganda. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To investigate the association between underweight and detectable viral load among adolescents living with HIV in rural eastern Uganda.

March 10, 2026Open Access

Underweight is associated with detectable viral load among adolescents with HIV in rural eastern Uganda: a retrospective cohort study

Key Points

To investigate the association between underweight and detectable viral load among adolescents living with HIV in rural eastern Uganda.
Retrospective cohort design
Population included adolescents with HIV in rural eastern Uganda
Assessment of nutritional status and viral load
Analysis of immunodeficiency levels
Detectable viral load (DVL) was nearly four times higher than the UNAIDS target
DVL was significantly linked to underweight and severe immunodeficiency
Emphasis on nutritional support and early HIV interventions was highlighted

Abstract

Among AWH in rural eastern Uganda, the prevalence of DVL was nearly four times the UNAIDS target of ≤ 5%. DVL was linked to underweight and severe immunodeficiency. Interventions such as nutritional support, targeted adherence counseling, early HIV diagnosis, and prompt ART initiation are critical to achieving viral suppression in this setting.

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