Tetahydrocurcumin-based copolymeric micellar hydrogel for improved dermal delivery

Key Points

• To develop and characterize tetrahydrocurcumin (THC) loaded micellar hydrogels for enhanced dermal delivery.
• Formulated micelles using monomethoxy poly(ethylene glycol)-poly(ẟ-valerolactone).
• Characterized micelles through X-ray diffraction and particle size analysis.
• Loaded micelles with 12.45% weight tetrahydrocurcumin.
• The THC-loaded micelles showed favorable particle size distribution.
• X-ray diffraction indicated successful incorporation of THC into the micelles.