Type 2 diabetes subphenotypes are associated with differential outcomes after metabolic and bariatric surgery: An international multicentre retrospective cohort study

Key Points

• The study aims to explore how different subphenotypes of type 2 diabetes (T2D) influence remission outcomes after metabolic and bariatric surgery (MBS).
• Conducted a multicenter retrospective cohort study.
• Analyzed remission rates of T2D subphenotypes after MBS.
• Compared outcomes between SIDD, MOD, and SIRD subphenotypes over a 2-year period.
• SIDD subphenotype exhibited significantly lower remission rates compared to MOD and SIRD.
• Differential outcomes highlight the importance of metabolic status in treatment decisions.