What question did this study set out to answer?

To establish a reliable measurement procedure for quantifying 17-hydroxyprogesterone in human samples.

March 13, 2026Clinical Chemistry and Laboratory Medicine (CCLM)1 citationsOpen Access

An isotope dilution-liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of 17-hydroxyprogesterone in human serum and plasma

MBMartina BachmannRoche Pharma AG (Germany)MOMyriam OttRoche Pharma AG (Germany)NSNeeraj SinghRoche Pharma AG (Germany)

Key Points

To establish a reliable measurement procedure for quantifying 17-hydroxyprogesterone in human samples.
Developed an isotope dilution-liquid chromatography-tandem mass spectrometry method.
Evaluated the performance and standardization of routine assays.
Assessed patient samples for measurement accuracy.
Enabled traceability for 17-hydroxyprogesterone measurements.
Improved the standardization of routine measurement assays.

Abstract

The performance of this procedure enables the evaluation and standardization of routine assays, and the evaluation of patient samples, to ensure traceability of individual patient results.

Demander à l'IA

Bookmark

View Full Paper

Cite This Study

Bachmann et al. (Wed,) studied this question.

synapsesocial.com/papers/69b3ac8102a1e69014cce49a https://doi.org/https://doi.org/10.1515/cclm-2025-1169

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

Demander à l'IA

Bookmark

View Full Paper