EXPRESS: Mechanism of asiatic acid in relieving psoriasis by modulating the PI3K/Akt/NF-κB pathway and NLRP3 inflammasome

Key Points

• This research aims to examine how asiatic acid modulates biological pathways to alleviate psoriasis symptoms.
• Investigated the effect of asiatic acid on psoriasis
• Analyzed the role of the PI3K/Akt/NF-κB pathway
• Assessed the involvement of the NLRP3 inflammasome
• Asiatic acid was found to block the PI3K/Akt/NF-κB pathway
• Significant reduction in psoriasis symptoms observed
• NLRP3 inflammasome activity was modulated by asiatic acid