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This research aims to investigate the cellular responses in human kidney tissue to BK polyomavirus infection.

March 15, 2026Open Access

Single-cell Analysis of Human Kidney Biopsy Tissue Reveals Epithelial and Immune Cell Responses to BK Polyomavirus Infection

This research aims to investigate the cellular responses in human kidney tissue to BK polyomavirus infection.
Conducted single-cell analysis of human kidney biopsy tissue
Identified immune and epithelial cell responses
Analyzed the implications for clinical management
Revealed distinct immune cell responses to BK polyomavirus
Observed significant epithelial cell changes due to infection
Suggested potential improvements in allograft management and outcomes

These not previously reported insights into BKV-associated injury may have implications for clinical management and improved allograft outcomes.

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Marvin et al. (Thu,) studied this question.

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