What does this research mean for the field?

Drug-induced toxicity, driven by altered pharmacokinetics, is a primary factor negatively impacting quality of life and increasing mortality in patients with end-stage renal disease undergoing dialysis. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

The aim is to understand the mechanisms and risk factors of drug-induced toxicity in patients undergoing renal dialysis.

March 22, 2026Open Access

Drug-Induced Toxicity in Patients Undergoing Renal Dialysis: Mechanisms, Risk Factors, and Management

Key Points

The aim is to understand the mechanisms and risk factors of drug-induced toxicity in patients undergoing renal dialysis.
Analyzed pharmacokinetics of drugs in patients with end-stage renal disease
Identified risk factors associated with drug toxicity
Evaluated strategies for managing drug-induced toxicity
Drug toxicity significantly impacts the quality of life in dialysis patients
Altered pharmacokinetics increases the risk of adverse drug reactions
Management strategies can reduce the incidence of drug-related complications

Abstract

In patients with end-stage renal disease (ESRD) on dialysis, drug toxicity caused by the drugs themselves is a primary factor affecting their quality of life and leading to death. Dialysis patients are characterized by altered pharmacokinetics which

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Drug-Induced Toxicity in Patients Undergoing Renal Dialysis: Mechanisms, Risk Factors, and Management

Key Points

Abstract

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