Increased MAP-1 and lectin complement activation capacity in Klinefelter syndrome

Key Points

• To investigate the immune function alterations associated with Klinefelter syndrome (KS).
• Evaluated MAP-1 and MASP1-201 expression levels in men with Klinefelter syndrome.
• Assessed lectin complement pathway activation capacity.
• Men with Klinefelter syndrome exhibited increased MAP-1 expression.
• There was a significant rise in MASP1-201 expression levels.
• The lectin complement pathway activation capacity was notably increased.