In exploratory modeling, organism type was the principal driver of resistance, though most organisms-antibiotic effects had wide confidence intervals.The most reliable association was lower tetracycline resistance in S. epidermidis (OR 0.012, 95% CI 0.0003-0.49;p=0.020).Dialysis modality and specimen type showed no independent association with resistance.Conclusion: Infections in CKD dialysis patients come from both catheter related or non related sources.K. pneumoniae, E. coli, and S. aureus are most common organisms.The resistance landscape showed high lactam and fluoroquinolone resistance in Enterobacterales and persistent MRSA.Organism type showed significant relations to resistance rather than dialysis modality or specimen source.The importance of empirical therapy based on organisms are highlighted in these findings and the need for dialysis-related antibiograms to optimize outcomes in interconnected kidney care.I have no potential conflict of interest to disclose.I did not use generative AI and AI-assisted technologies in the writing process.
Helal et al. (Wed,) studied this question.