Evaluation of a genetically attenuated Cryptosporidium parvum strain in the calf clinical model of cryptosporidiosis

Key Points

• This research aims to assess the effectiveness of genetically attenuated C. parvum strains using a neonatal calf model.
• Utilized a neonatal calf model to test genetically attenuated C. parvum strains.
• Evaluated the calves for signs of cryptosporidiosis post-challenge.
• Facilitated future challenge studies to enhance understanding of strains' effects on disease.
• Demonstrated the neonatal calf model's effectiveness in evaluating C. parvum strains.
• Provided insights for future studies focusing on reducing diarrheal disease.