Cuproptosis in spinal cord injury: emerging mechanisms and immunological relevance

Key Points

• Investigate cuproptosis mechanisms in spinal cord injury and their impact on the immune response.
• Explored cuproptosis pathways involved in secondary injury after spinal cord damage.
• Analyzed the immune microenvironment changes related to cuproptosis.
• Evaluated potential therapeutic strategies targeting copper homeostasis.
• Identified cuproptosis as a significant factor in immune remodeling following spinal cord injury.
• Demonstrated that restoring copper levels may enhance healing processes and immune responses.