Acquired Subglottic Cyst in a Premature Infant Following Recurrent Intubation: A Case Report

Acquired subglottic cysts are retention cysts that develop as a consequence of iatrogenic trauma to the subglottic mucosa. They are most commonly observed in neonates with a history of prematurity and repeated endotracheal intubation. These cysts may lead to nonspecific symptoms of airway obstruction, such as persistent stridor. We present the case of a premature infant born at 26 weeks of gestation who developed an acquired subglottic cyst following multiple episodes of intubation for recurrent respiratory distress. After persistent respiratory symptoms and an unsuccessful attempt at bronchoscopy, further evaluation using direct laryngoscopy confirmed the presence of a subglottic cyst. This case highlights the importance of recognizing this uncommon but clinically significant condition in premature infants and emphasizes the need for a multidisciplinary approach in diagnosis and management to prevent potentially serious airway complications. It also explores the association between prematurity, low birth weight, and prolonged airway support in the development of subglottic cysts, highlighting the need for further research in this area.