This work presents a hypothesis that variation in environmental radiation exposure may influence mutation landscapes in biological systems. While radiation is a recognised mutagenic factor, this manuscript proposes that differences in radiation environments may systematically modulate the distribution and characteristics of genetic variation through effects on DNA damage and repair processes. This may introduce environment-dependent biases in mutation patterns, shaping the substrate upon which natural selection operates. A testable experimental framework is outlined using controlled radiation conditions and genomic analysis of mutation spectra. This is a preprint and has not undergone peer review.
Singh Rajinder Pal (Sun,) studied this question.