Apixaban therapy partially resolved linear white thrombi and completely eliminated a cleft in the abnormal proximal ascending aortic wall in a 63-year-old male patient.
Case Report (n=1)
No
Apixaban therapy may partially resolve linear thrombi and structural clefts in the ascending aortic wall associated with an atypical right coronary artery supply to pericardial adipose tissue.
A 63-year-old male patient with chronic obstructive pulmonary disease (COPD) was examined using cardiac computed tomography (CT) and transesophageal echocardiography (TEE) to estimate the presence of chronic thrombi, such as left atrial appendage (LAA) thrombi and pulmonary vein thrombi (PVTs). The patient presented with a strange thrombus-containing vessel over the anterior surface of the heart, which did not appear to be a coronary vein. The abnormal wall of the ascending aorta (AAo) was difficult to differentiate from the AAo thrombi, and a dark (low echogenic) mass was observed in the center of the abnormal AAo wall on TEE. The origin of the mass was unknown but could potentially be associated with atherosclerosis, a Valsalva aneurysm, aortic dissection, an aortic aneurysm, or aortic valve disease. The relationship between these factors and the coronary artery, as well as whether apixaban (a factor Xa inhibitor) could cure the cleft in the mass, remains unclear.
Hidekazu Takeuchi (Sun,) conducted a case report in Abnormal proximal ascending aortic wall with thrombi and COPD (n=1). Apixaban was evaluated on Resolution of thrombi and ascending aortic wall cleft assessed by transesophageal echocardiography. Apixaban therapy partially resolved linear white thrombi and completely eliminated a cleft in the abnormal proximal ascending aortic wall in a 63-year-old male patient.