Meibum Lipid Saturation Related to Dry Eye, Age, and Sex Using Nuclear Magnetic Resonance Spectroscopy

Key Points

• To investigate how meibum lipid saturation is related to dry eye, age, and sex.
• Utilized nuclear magnetic resonance spectroscopy to analyze meibum lipids.
• Compared lipids in cohorts with and without dry eye.
• Evaluated the effect of age and sex on lipid saturation levels.
• Observed decreased meibum HCunsat in dry eye and associated conditions.
• Found that HCunsat levels decrease with age.
• Identified lipid saturation as a contributing factor to meibomian gland dysfunction.

Abstract