Surface functionalized binary antibiotic nanoparticles of enhanced antimicrobial action

Key Points

• The research aims to understand how enhanced surface functionalization can improve the antimicrobial properties of antibiotic nanoparticles.
• Produced binary antibiotic nanoparticles through coprecipitation of anionic and cationic antibiotics.
• Utilized a surface-active polymer for stabilization.
• Incorporated a long-chain cationic surfactant to enhance properties.
• Significantly increased antimicrobial action compared to non-functionalized nanoparticles.
• Demonstrated effectiveness against various bacterial strains.