What question did this study set out to answer?

This research aims to evaluate the effectiveness of dupilumab in real-world settings for patients with severe asthma.

April 1, 2026Open Access

Real-World Experience With Dupilumab in Severe Asthma: The Spanish Multicenter Study DUPImpact

Key Points

This research aims to evaluate the effectiveness of dupilumab in real-world settings for patients with severe asthma.
Multicenter study design
Assessment of exacerbations and oral corticosteroid (OCS) use
Evaluation of asthma control and lung function
Utilization of FEOS and EXACTO for multidimensional assessment
Dupilumab significantly reduced asthma exacerbations
Patients showed decreased use of oral corticosteroids (OCS)
Improvements in asthma control were noted
Lung function enhanced as measured through objective tests

Abstract

The DUPImpact study confirms the real-world effectiveness of dupilumab in reducing exacerbations and OCS use and improving asthma control and lung function. FEOS and EXACTO enable a multidimensional assessment beyond individual measures.

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Authors

Hemily Izaguirre-Flores

Universidad de La Laguna

Ebymar Arismendi

Elena Martín-Ruiz de la Rosa

Journals

Journal of Investigational Allergology and Clinical Immunology

Actions

Institutions

Universitat de Barcelona

Hospital Clínic de Barcelona

Instituto de Salud Carlos III

References and Citations

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Real-World Experience With Dupilumab in Severe Asthma: The Spanish Multicenter Study DUPImpact

Key Points

Abstract

Citation Network

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Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

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