Histopathological analysis of stent thrombosis reveals a strong inflammatory and potentially allergic component, driven by neutrophils, NETs, and eosinophils.
In a large-scale study of histological thrombus analysis from patients presenting with ST, thrombus specimens displayed heterogeneous morphology. Recruitment of leukocytes, particularly neutrophils, appears to be a hallmark of ST. The presence of NETs supports their pathophysiological relevance. Eosinophil recruitment suggests an allergic component to the process of ST.
Riegger et al. (Sun,) studied this question.