Does pulsed field ablation prevent chronic atrial fibrotic changes and restrictive mechanics after catheter ablation for atrial fibrillation?
Pulsed field ablation for atrial fibrillation appears to involve a reparative process with less chronic fibrosis, potentially preserving left atrial compliance and function.
Pulsed field ablation induces large acute LGE without microvascular damage or intramural haemorrhage. Most LGE lesions disappear in the chronic stage, suggesting a specific reparative process involving less chronic fibrosis. This process may contribute to a preserved tissue compliance and LA reservoir and booster pump functions.
Nakatani et al. (Thu,) studied this question.
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