What question did this study set out to answer?

The aim is to evaluate the success rates of bacterial cellulose-enhanced MTA compared to conventional MTA in indirect pulp capping for primary teeth.

April 8, 2026Open Access

Bacterial cellulose–enhanced MTA versus conventional MTA for indirect pulp capping in primary teeth: a randomized controlled clinical trial

Key Points

The aim is to evaluate the success rates of bacterial cellulose-enhanced MTA compared to conventional MTA in indirect pulp capping for primary teeth.
Randomized controlled trial design with 40 primary molars
Patients divided into two groups: one receiving BC-MTA and the other conventional MTA
Follow-up evaluations at 3 and 9 months post-treatment
Clinical and radiographic assessment of success rates
Data analyzed using descriptive statistics and Chi-square tests
75% of cases reported complete pain relief after 9 months
Internal root resorption occurred in 2 teeth in the BC-MTA group
Overall success rates: 88.23% for BC-MTA and 100% for conventional MTA
Both materials showed favorable outcomes for indirect pulp capping in primary teeth

Abstract

This randomized controlled trial aimed to compare the clinical and radiographic success rates of bacterial cellulose-reinforced MTA (BC-MTA) and conventional MTA in indirect pulp capping (IPT) treatment of primary teeth. A total of 40 primary molars diagnosed for IPT were randomly allocated into two groups: Group I (BC-MTA, n = 20) and Group II (Conventional MTA, n = 20). IPT procedures were carried out under aseptic conditions following local anesthesia, and teeth were restored with glass ionomer cement (GIC). Follow-up evaluations were performed clinically and radiographically at 3 and 9 months postoperatively. Data were analyzed using IBM SPSS Statistics 20, applying descriptive statistics, Chi-square, and independent t-tests (p < 0.05). At the end of 9 months, 75% of cases reported complete pain relief. Internal root resorption was observed in two teeth in Group I. Overall success rates at 9 months were 88.23% for BC-MTA and 100% for conventional MTA. Both BC-MTA and MTA showed favorable and comparable outcomes in IPT of primary teeth. While BC-MTA demonstrates potential due to its biocompatibility and improved handling characteristics, further studies are needed to validate its long-term clinical efficacy.Trial Registration: Ethical clearance was granted by SRM University IEC (SRMIEC-ST0323-442) and registered retrospectively in CTRI (CTRI/2024/12/077670).

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