March 8, 2011Open Access

Left Ventricular Lead Position and Clinical Outcome in the Multicenter Automatic Defibrillator Implantation Trial–Cardiac Resynchronization Therapy (MADIT-CRT) Trial

JSJagmeet P. SinghElectrophysiology HKHelmut KleinElectrophysiology DHDavid T. HuangElectrophysiology

Structured PICO

Does apical left ventricular lead position affect clinical outcomes in patients receiving cardiac resynchronization therapy?

Population

Patients undergoing cardiac resynchronization therapy in the Multicenter Automatic Defibrillator Implantation Trial-Cardiac Resynchronization Therapy (MADIT-CRT)

Intervention

Apical left ventricular lead position

Outcome

Clinical outcome

Apical positioning of left ventricular leads in cardiac resynchronization therapy is associated with unfavorable outcomes and should be avoided.

Abstract

LV leads positioned in the apical region were associated with an unfavorable outcome, suggesting that this lead location should be avoided in cardiac resynchronization therapy. Clinical Trial Registration- URL: http://clinicaltrials.gov. Unique identifier: NCT00180271.

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