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Both flow and microstructure apparently contribute to the medullary diffusion anisotropy. The described novel method may be useful in separating decreased tubular flow from irreversible structural tubular damage, for example, in diabetic nephropathy or during allograft rejection.
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Mike Notohamiprodjo
University of Tübingen
Hersh Chandarana
Centre d'Imagerie BioMedicale
Artem Mikheev
Advanced Imaging Research (United States)
Magnetic Resonance in Medicine
University of Utah
University of Tübingen
NYU Langone Health
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Notohamiprodjo et al. (Mon,) studied this question.
synapsesocial.com/papers/69d71eb4ef370a38abf50aaa — DOI: https://doi.org/10.1002/mrm.25245