Does a restrictive fluid regimen improve disability-free survival in patients at increased risk for complications during major abdominal surgery?
In high-risk patients undergoing major abdominal surgery, a restrictive fluid regimen does not improve disability-free survival and increases the risk of acute kidney injury compared to a liberal fluid regimen.
Among patients at increased risk for complications during major abdominal surgery, a restrictive fluid regimen was not associated with a higher rate of disability-free survival than a liberal fluid regimen and was associated with a higher rate of acute kidney injury. (Funded by the Australian National Health and Medical Research Council and others; RELIEF ClinicalTrials.gov number, NCT01424150 .).
Myles et al. (Thu,) studied this question.
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