September 16, 2023Open Access

Exosomes derived from LPS-preconditioned bone marrow-derived MSC modulate macrophage plasticity to promote allograft survival via the NF-κB/NLRP3 signaling pathway

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Abstract

LPS pre-Exo are able to switch the polarization of macrophages and enhance the resolution of inflammation. This type of exosomes provides an improved immunotherapeutic potential in prolonging graft survival.

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Zhang et al. (Sat,) studied this question.

synapsesocial.com/papers/69d7baa305ee2ba81dbed8b9 https://doi.org/https://doi.org/10.1186/s12951-023-02087-8

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