September 29, 2020Open Access

RNA N6-methyladenosine reader IGF2BP3 regulates cell cycle and angiogenesis in colon cancer

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Abstract

Knockdown of IGF2BP3 repressed DNA replication in the S phase of cell cycle and angiogenesis via reading m6A modification of CCND1 and VEGF respectively. IGF2BP3 was a possible prognosis marker and potential therapeutic target of colon cancer.

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Zhou et al. (Tue,) studied this question.

synapsesocial.com/papers/69d7e2ebec32c73b01ae32cf https://doi.org/https://doi.org/10.1186/s13046-020-01714-8

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