June 4, 2015Open Access

Identification of an anti-inflammatory protein from Faecalibacterium prausnitzii , a commensal bacterium deficient in Crohn’s disease

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Abstract

A 15 kDa protein with anti-inflammatory properties is produced by F. prausnitzii, a commensal bacterium involved in CD pathogenesis. This protein is able to inhibit the NF-κB pathway in intestinal epithelial cells and to prevent colitis in an animal model.

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Quévrain et al. (Thu,) studied this question.

synapsesocial.com/papers/69d7ec4911d83f35e5ae33fc https://doi.org/https://doi.org/10.1136/gutjnl-2014-307649

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