Does the CHA2DS2-VASc score improve stroke and thromboembolism risk stratification compared to the CHADS2 score in patients with atrial fibrillation?
While both scores have similar overall predictive utility, the CHA2DS2-VASc score is superior for identifying truly low-risk patients with atrial fibrillation.
The C-statistic suggests a similar clinical utility of the CHADS2 and CHA2DS2-VASc scores in predicting stroke and thromboembolism, but CHA2DS2- VASc has the important advantage of identifying extremely low-risk patients with atrial fibrillation, as well as classifying a lower proportion of patients as moderate risk.
Chen et al. (Sun,) studied this question.