Comparative effectiveness of antiviral therapy according to immune status among pregnant women with chronic hepatitis B virus infection: a retrospective cohort study

Key Points

• To evaluate the effectiveness of antiviral therapy in managing chronic hepatitis B virus (HBV) infection among pregnant women based on their immune status.
• Retrospective cohort study design
• Comparison of antiviral therapy outcomes based on immune status
• Focus on TDF (tenofovir disoproxil fumarate) efficacy
• TDF demonstrated effective suppression of viral replication in pregnant women with HBV
• Findings indicate safety for both mother and fetus
• TDF was particularly beneficial for historically undertreated subgroups