Characterization of Pulmonary Dysfunction in Systemic Juvenile Idiopathic Arthritis Using Xenon and Proton MRI

Key Points

• To characterize pulmonary dysfunction in systemic juvenile idiopathic arthritis (SJIA) using advanced MRI techniques.
• Utilized xenon and proton MRI to assess lung abnormalities in SJIA
• Analyzed RBC/Membrane signals for pulmonary diffusion limitation
• Explored potential for longitudinal monitoring of lung function changes
• Identified specific pulmonary abnormalities associated with SJIA
• Demonstrated RBC/Membrane as a promising indicator of diffusion limitation
• Highlighted the capability of MRI for future phenotyping of SJIA-related lung issues