Breakthrough Mold Infections During Long-term Nebulized Liposomal Amphotericin B Prophylaxis in Lung Transplant Recipients: A Single-center Cohort (NEBULA Study)

Key Points

• To evaluate the incidence of mold infections in lung transplant recipients on nebulized liposomal amphotericin B prophylaxis.
• Conducted a single-center cohort study
• Followed lung transplant recipients undergoing n-LAB prophylaxis
• Monitored incidence of mold infections and tolerance over time
• Low incidence of mold infections reported
• Nonsusceptible molds did not increase mortality
• Excellent tolerability of n-LAB prophylaxis maintained over prolonged follow-up