February 17, 2017

Gut microbial profile is altered in primary biliary cholangitis and partially restored after UDCA therapy

RTRuqi TangShanghai Jiao Tong University YWYiran WeiUniversity of Science and Technology of China YLYanmei LiCenter for Drug Evaluation and Research

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Abstract

This study presents a comprehensive landscape of gut microbiota in PBC. Dysbiosis was found in the gut microbiome in PBC and partially relieved by UDCA. Our study suggests that gut microbiota is a potential therapeutic target and diagnostic biomarker for PBC.

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