July 11, 2013Open Access

Visualization of nigrosome 1 and its loss in PD

Key Points

Key points are not available for this paper at this time.

Abstract

In vivo and PM MRI with histologic correlation demonstrates that high-resolution 7 T MRI can directly visualize nigrosome 1. The absence of nigrosome 1 in the SNpc on MRI scans might prove useful in developing a neuroimaging diagnostic test for PD.

Bookmark

View Full Paper

Bookmark

View Full Paper

Cite This Study

Blazejewska et al. (Thu,) studied this question.

synapsesocial.com/papers/69d8f80b6715230d10bedce9 https://doi.org/https://doi.org/10.1212/wnl.0b013e31829e6fd2

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Quantification of histochemical staining by color deconvolution.2001 · 2,065 citations
2Leaching of Trace Elements from Biological Tissue by Formalin Fixation2007 · 81 citations
3Nigrosome imaging with T2*-weighted 3T MRI as a diagnostic marker of Parkinson's disease: a case-control and cross-sectional study of diagnostic accuracy2014 · 9 citations
4Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases.1992 · 10,429 citations
5Assessment of relative brain iron concentrations using T2‐weighted and T2*‐weighted MRI at 3 Tesla1994 · 325 citations